$validator = Validator::make($request->all(), [
'Picture' => 'required|image|mimes:jpeg,bmp,png,gif,PNG,jpg',
// Picture is name of file you set in [...]
Here is example for upload file in larave :
public function user()
{
$user = new User;
$form_input = Input::all();
if (Input::hasFile('Picture')) { [...]